Search our medical news database advanced search register login hot topics aging biotechnology breast cancer women's health allergies more home newsletter for purchase medical topics products about us contact verticalnews monoclonal gammopathy igm monoclonal gammopathy increases the risk for lymphoma and other diseases published in blood weekly , january 22nd, 2004 igm monoclonal gammopathy increases the risk for lymphoma and other diseases. "little effort has been made to quantitate adverse outcomes of monoclonal gammopathy of undetermined significance (mgus) of the immunoglobulin m (igm) class, which progresses to lymphoma or waldenstrom macroglobullnemia, whereas iga and igg mglis progress to multiple myeloma, primary amyloiclosis (al), or a related plasma cell disorder," scientists writing in the journal blood report. "from 1960-1994, igm mgus was diagnosed in 213 patients in southeastern minnesota. The end point was progression to lymphoma or a related disorder, as assessed with the kaplan-meier method. "the 213 patients were followed up for 1567 person-years (median, 6. 3 yrs per patient). Lymphoma developed in 17 patients (relative risk [rr], 14. 8), waldenstrom macroglobulinemia in 6 (rr, 262), primary amyloiclosis in 3 (rr, 16. cheap viagra for sale 3), and chronic lymphocytic leukemia in 3 (rr, 5. 7). " the doctors affirmed: "the relative risk of progression was 16-fold higher in the patients with igm mgus than in the white population of the iowa surveillance, epidemiology, and end results program.